• Alliance Reports Results from First Randomized Trial of a Radiopharmaceutical in Kidney Cancer

    RadiCaL study results show adding bone-targeting radium-223 to cabozantinib does not improve symptomatic skeletal-related events, highlighting the value of current standard treatments to optimize bone health for patients with bone metastases. Results from the Alliance for Clinical Trials in Oncology’s Phase II RadiCaL trial (Alliance A031801), the first randomized study of a radiopharmaceutical in kidney…

  • Alliance SOLARIS Trial: Vitamin D3 Fails to Boost Colorectal Cancer Survival

    For patients with advanced colorectal cancer, adding high-dose vitamin D3 to standard first-line treatment does not improve progression-free survival, according to the results from the Phase III SOLARIS trial (Alliance A021703) published in the Journal of the American Medical Association. Experimental evidence has suggested that vitamin D may have antineoplastic activity, including effects on tumor…

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