May 19, 2026 – The Alliance for Clinical Trials in Oncology has launched a new clinical research study to explore whether a more targeted form of radiation therapy lowers the chance of lung cancer returning after surgery. The study (Alliance A082402) is for people with non‑small cell lung cancer (NSCLC) who underwent chemotherapy and immunotherapy…
The ERASur (Evaluation of Resection or Ablation for Limited Metastatic Colorectal Cancer) clinical trial has reached a major enrollment milestone, with more than one-third of its targeted patients now accrued, signaling strong momentum for this national study. ERASur (Alliance A022101) is investigating whether adding total ablative therapy—including ablative radiation, surgery, or thermal ablation of all metastatic sites—to…
Highlighting Alliance Progress and Impact in Research through News Reports At the Alliance for Clinical Trials in Oncology, we love sharing stories that show what’s happening in cancer research right now. Whether it’s a new clinical trial, a scientific breakthrough, or the work of one of our dedicated investigators, we want people to see the…
Did you know that cancers in the head and neck area, including the mouth, throat, nasal cavity and voice box, account for about 4% of all new cancers diagnosed in U.S. each year? Major risk factors include smoking cigarettes as well as the use of smokeless tobacco (chewing tobacco and vaping) and alcohol. People with…
The Alliance for Clinical Trials in Oncology is now enrolling patients into a clinical trial aimed at helping women recover from the vaginal side effects of breast cancer treatment. Supported in part by a grant from the National Cancer Institute, the REVITALIZE study (Alliance A221801) will test if a laser therapy helps reduce vaginal dryness…
April 8, 2026 – A randomized trial conducted by the Alliance for Clinical Trials in Oncology with support from the National Cancer Institute has found that duloxetine, a medication commonly used to treat chronic pain and psychiatric conditions, does not prevent nerve damage caused by chemotherapy in patients with colorectal cancer. The primary analysis of Alliance A221805 was…
Each year, about 85,000 adolescents and young adults (AYA) between the ages of 15 and 39 are diagnosed with cancer in the United States. According to the National Cancer Institute, this represents about 4% of all new cancer diagnoses. Depending on age and specific diagnosis, many AYA people with cancer may be treated at either…
A new clinical trial led by the Alliance for Clinical Trials in Oncology will investigate if a combination of drug therapies after radiation therapy improves outcomes for people with newly-diagnosed, grade 3 IDH-mutant astrocytoma, a type of brain cancer. Supported in part by a grant from the National Cancer Institute, the study (Alliance A072301) will…
The Alliance for Clinical Trials in Oncology has launched a new clinical trial for adults who need first-line therapy for chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL). The study (Alliance A042302) will explore whether combining two targeted medicines, zanubrutinib and sonrotoclax, can effectively send cancer into remission, allowing patients to discontinue treatment until…
In time for Colorectal Cancer Awareness Month in March, the Alliance for Clinical Trials in Oncology has launched a new clinical study aimed at helping improve how patients with colorectal cancer share information about the genetic risks to their family members. Supported by grants from the National Cancer Institute, the trial, “Family Communications After Genetic…
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