Zoledronic Acid in Treating Patients With Metastatic Breast Cancer, Metastatic Prostate Cancer, or Multiple Myeloma With Bone Involvement
Study Information
Alliance Study ID: CALGB-70604
NCT Study ID (ClinicalTrials.gov): NCT00869206
Alliance Committee: Cancer Control
Disease or Cancer Type: Breast Cancer, Multiple Myeloma & Plasma Cell Disorders, Prostate Cancer
Alliance Study Chair: Andrew L. Himelstein, MD
Status: COMPLETED
Study Description
This randomized phase III trial studies two different schedules of zoledronic acid to compare how well they work in reducing bone-related complications in patients with breast cancer, prostate cancer, or multiple myeloma that has spread to other places in the body and have bone involvement. Bone-related complications are a major cause of morbidity in patients with metastatic prostate cancer, breast cancer, and multiple myeloma. Zoledronic acid may stop the growth of cancer cells in the bone and may help relieve some of the symptoms caused by bone metastases. It is not yet known whether giving zoledronic acid more or less frequently is more effective in treating patients with metastatic cancer that has spread to the bone.
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