Temozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by Surgery
Study Information
Alliance Study ID: NCCTG-N0675
NCT Study ID (ClinicalTrials.gov): NCT00521001
Disease or Cancer Type: Melanoma & Skin Cancers
Alliance Study Chair: Ravi D. Rao, MD, MBBS
Status: COMPLETED
Study Description
RATIONALE: Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Everolimus may stop the growth of tumor cells by blocking blood flow to the tumor and by blocking some of the enzymes needed for cell growth. Giving everolimus together with temozolomide may kill more tumor cells.
PURPOSE: This phase II trial is studying how well giving everolimus together with temozolomide works in treating patients with stage IV melanoma that cannot be removed by surgery
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