Study Information

Alliance Study ID: CALGB-9781

NCT Study ID (ClinicalTrials.gov): NCT00003118

Alliance Committee: Gastrointestinal Cancer

Disease or Cancer Type: Gastrointestinal Cancers – Pancreatic / Gastric / Esophageal / Liver / Biliary

Alliance Study Chair: Mark Krasna, MD

Status: COMPLETED


Study Description

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether surgery is more effective with or without chemotherapy and radiation therapy for cancer of the esophagus.

PURPOSE: Randomized phase III trial to compare the effectiveness of surgery with or without combination chemotherapy and radiation therapy in treating patients who have cancer of the esophagus that can be surgically removed.

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