Study Information

Alliance Study ID: AFT-50

NCT Study ID (ClinicalTrials.gov): NCT04486352

Alliance Committee: Genitourinary Cancer

Disease or Cancer Type: Gynecologic Cancers – Ovarian / Uterine / Cervical / Endometrial

Alliance Study Chair: Brian Slomovitz, MD

Status: RECRUITING


Study Description

This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune checkpoint therapy with atezolizumab in participant with recurrent and/or persistent endometrial cancer. The main protocol provides a platform for genomic screening with homogeneous basic eligibility criteria in order to direct study participants into biomarker-matched study cohorts consisting of testing targeted agents.

Related Publications

For publications related to this and other clinical trials, visit the Alliance Publications Application.

Locations (21)

City of Hope Comprehensive Cancer Center
Duarte, California 91010
United States

UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco, California 94143
United States

Medstar Georgetown Cancer Institute
Washington D.C., District of Columbia 20007
United States

Mount Sinai Comprehensive Cancer Center
Miami Beach, Florida 33140
United States

University of Chicago
Chicago, Illinois 60637
United States

University of Kansas Cancer Center
Westwood, Kansas 66205
United States

Maine Medical Center
Scarborough, Maine 04074
United States

Dana Farber Cancer Institute
Boston, Massachusetts 02125
United States

University of Minnesota
Minneapolis, Minnesota 55455
United States

Washington University School of Medicine Siteman Cancer Center
St Louis, Missouri 63110
United States

Nebraska Methodist Hospital
Omaha, Nebraska 68114
United States

Englewood Health
Englewood, New Jersey 07631
United States

Atlantic Health Systems/Morristown Medical Center
Morristown, New Jersey 07960
United States

Roswell Park
Buffalo, New York 14263
United States

Weill Cornell Medicine
New York, New York 10065
United States

Duke University Cancer Center
Durham, North Carolina 27710
United States

University of Oklahoma Health Stephenson Cancer Center
Oklahoma City, Oklahoma 73104
United States

Providence Portland Cancer Institute
Portland, Oregon 97213
United States

University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania 15261
United States

Lifespan – Rhode Island Hospital
Providence, Rhode Island 02903
United States

Baptist Memorial Hospital
Memphis, Tennessee 38120
United States

Data Sources & Contacts

Related Alliance Trials