Study Information

Alliance Study ID: ACOSOG-Z0300

NCT Study ID (ClinicalTrials.gov): NCT00030628

Alliance Committee: Neuro-Oncology

Disease or Cancer Type: Brain / Central Nervous System Cancer

Alliance Study Chair: Anthony Asher, MD, FACS

Status: COMPLETED


Study Description

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Radiosurgery may be able to deliver x-rays directly to the tumor and cause less damage to normal tissue. It is not yet known if radiosurgery is more effective with or without whole-brain radiation therapy in treating brain metastases.

PURPOSE: Randomized phase III trial to compare the effectiveness of radiosurgery with or without whole-brain radiation therapy in treating patients who have brain metastases.

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