Study Information

Alliance Study ID: CALGB-9741

NCT Study ID (ClinicalTrials.gov): NCT00003088

Alliance Committee: Breast Cancer

Disease or Cancer Type: Breast Cancer

Alliance Study Chair: Marc L. Citron, MD

Status: COMPLETED


Study Description

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving drugs at different times or combining more than one drug may kill more tumor cells. It is not yet known which chemotherapy regimen is more effective for breast cancer.

PURPOSE: Randomized phase III trial to compare the effectiveness of chemotherapy consisting of either doxorubicin, cyclophosphamide, or paclitaxel given at different times with that of combination chemotherapy consisting of doxorubicin plus cyclophosphamide followed by paclitaxel in treating women with stage II or stage IIIA breast cancer.

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