Study Information

Alliance Study ID: NCCTG-N0432

NCT Study ID (ClinicalTrials.gov): NCT00088998

Disease or Cancer Type: Breast Cancer

Alliance Study Chair: Edith A. Perez, MD

Status: COMPLETED


Study Description

RATIONALE: Drugs used in chemotherapy, such as docetaxel and capecitabine, work in different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as bevacizumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Bevacizumab may also stop the growth of tumor cells by stopping blood flow to the tumor. Combining chemotherapy with monoclonal antibody therapy may kill more tumor cells.

PURPOSE: This phase II trial is studying how well giving docetaxel and capecitabine together with bevacizumab works in treating patients with metastatic breast cancer.

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