Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer
Study Information
Alliance Study ID: CALGB-9481
NCT Study ID (ClinicalTrials.gov): NCT00002716
Alliance Committee: Gastrointestinal Cancer
Disease or Cancer Type: Colorectal / Colon / Rectal Cancer
Alliance Study Chair: Nancy E. Kemeny, MD
Status: COMPLETED
Study Description
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which chemotherapy regimen is more effective for metastatic colorectal cancer.
PURPOSE: Randomized phase III trial to compare the effectiveness of intrahepatic floxuridine, leucovorin, and dexamethasone with that of systemic fluorouracil and leucovorin in treating patients who have unresectable liver metastases from colorectal cancer.
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